Non-metastatic adenocarcinoma of the appendix, often found incidentally after routine appendectomy, is a rare cancer whose subsequent management still is debated. It is classified into two general categories: mucinous and non-mucinous adenocarcinoma of the appendix (NMACA). The behavior of NMACA, considered similar to that of colon adenocarcinoma, exhibits more aggressive growth and has high rates of lymph node (LN) metastasis.
The management of NMACA involves performing a formal right hemicolectomy (RHC), not only to obtain a margin negative resection, but also to achieve optimal lymph node sampling for appropriate staging.